Mandra Bella is of local architectural and historical significance.
Historically, the property is a remnant of one of the larger semi-rural subdivisions predating 20th century suburban subdivision of Heidelberg. In this regard the orientation of the house away from Carlsberg Road and the numerous surviving outbuildings are of interest. The house is largely intact, and is enhanced by its mature landscaped setting.
Of local historical interest is the connection with various members of the MrCormick family, including William McCormick, station master for 40 years at Flinders Street Station during the late 19th and early 20th centuries, and Renee McCormick, a prominent female member of the architectural profession during the 1940s, 50s and 60s.