Wentworth House is included on the Victorian Heritage Register (H0138) as a place of State significance. Please refer to the VHR citation for the statement of significance for this place. The local statement of significance is as follows:
Wentworth House is of state historical and architectural importance. The original section of this structure, constructed only seven years after the foundation of the colony at Port Phillip, is one of the oldest surviving house in Victoria to remain on its original site. The property has strong associations with several pioneer agriculturists in the district, it is an important and rare illustration of early Victorian colonial traditions.